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Under the epidemic situation, how to choose the helicobacter pylori detection?

时间:2020-04-20     

At the present, novel coronavirus novel coronavirus infection has ravaged the world, while the number of infections grows with each passing day. After the outbreak, Antai has listed the new IgA/IgM/IgG antibody combination detection kit (colloidal gold) immediately, to provide the latest weapon for global epidemic prevention and clinical detection. 


Although the domestic epidemic situation in China has eased, the public still needs to wear a mask when going out, especially in hospitals, to avoid getting infected. Some patients will choose the breath test method when they go to the hospital to detect Helicobacter pylori. Because of wearing masks, it is not convenient to take off the masks and blow. At this time, we advocate choosing the serum antibody complementary to a breath test to detect Hp. Only a drop of peripheral blood is needed to complete the rapid detection. 


After several years, Hp serological antibody detection has been recognized by medical institutions, experts and the public. 


"The Fifth National Consensus Report on the Treatment of Helicobacter pylori Infection" strengthened the preventive effect of Hp eradication on gastric cancer, pointing out that Hp infection is the most important controllable risk factor for the prevention of gastric cancer, and Hp eradication can be used as a primary prevention measure for gastric cancer. However, the fifth expert consensus indicated that the clinical application of routine serological detection of HP antibody was limited. 


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Statement on serological detection of Hp antibody in the fifth consensus of experts


However, in the latest "expert consensus on eradication of Helicobacter pylori and prevention and control of gastric cancer in China (Shanghai, 2019)", it was clearly pointed out that HP serological detection could be carried out simultaneously with pepsinogen and gastrin-17, which was suitable for gastric cancer screening. In 2019, the consensus of Chinese experts in Shanghai fully affirmed the role of serological detection of Hp. 


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Statement of Hp screening methods in 2019 Shanghai China expert consensus


In 2019, the release of consensus among Chinese experts in Shanghai indicated that both scientific experts and medical institutions were aware of the close relationship between Helicobacter pylori and gastric cancer, and the early detection and treatment of gastric cancer had the equal importance to reduce the mortality of gastric cancer. As we have known, China is a country with a high incidence of gastric cancer, and 70-90% of gastric cancer patients are in advanced or late-stage when they are found, with poor prognosis. It has been proved that the prognosis of patients who are found and treated in the early stage is efficient. As a diagnostic medical technology enterprise, Antai has long been focusing on major diseases and providing advanced diagnostic technology and products. In the marketing promotion of detection of Helicobacter pylori, it actively advocates the public improve the awareness of gastric cancer risk factors and gastric cancer screening, popularize the relevant knowledge of gastric cancer and its prevention, early detection and eradication of Helicobacter pylori, and reduce the incidence and disease of gastric cancer Death rate. The new consensus affirms the importance of Helicobacter pylori serological detection for gastric cancer screening, marking that our promotion work has achieved a stage victory. It is worth doing a good job of Helicobacter pylori detection for the benefit of the country and the people. 


There is no doubt that Helicobacter pylori infection plays an essential role in the occurrence of gastric cancer. In recent years, both domestic and international experts' consensus have shown that eradicating Hp can significantly reduce the risk of gastric cancer.


The diagnostic value of Helicobacter pylori in gastric cancer screening has been gradually recognized in clinical application. For instance, the laboratory of Fushun Mining Bureau General Hospital in Liaoning Province recently published an article entitled "the diagnostic value of Helicobacter pylori specific IgM and IgG antibodies, CA724 and CEA combined detection for early gastric cancer". 


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The article is published in the 8th issue of China Medical Guide, March 2020.


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The colloidal gold test kit mentioned in this paper is a combined IgM / IgG antibody test kit for Helicobacter pylori developed and produced exclusively by Antai. The kit showed stable quality and excellent performance in this study. The results show that Helicobacter pylori infection is an important factor in the pathogenesis of gastric cancer. The specific IgM and IgG antibodies of Helicobacter pylori can be used as important serological indexes in early gastric cancer screening, and the combined detection can improve the sensitivity of gastric cancer diagnosis, effectively avoid the missed diagnosis, and provide an important basis for the early diagnosis of gastric cancer. 


Understanding Hp

Helicobacter pylori is essentially a bacterium because it produces substances that neutralize stomach acid, giving it a bulletproof protective suit, so it can take root and grow on the surface of our stomach mucosa without being killed by the acid. Helicobacter pylorus is also the only organism known to colonize the human stomach. 


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The investigation showed that the national average infection rate of Helicobacter pylori was about 58%, the detection rate of Hp in gastric ulcer patients was about 80%, the detection rate of Hp in duodenal ulcer patients was about 95%, and the infection rate of Hp in gastric cancer patients was about 89%. 


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The following symptoms indicate the possibility of helicobacter pylori infection: 


Archenteron symptoms

Hp stimulates the stomach and intestinal mucosa; hence it will show typical gastrointestinal symptoms, mainly peptic ulcer and dyspepsia. Patients with Hp infection will show a feeling of fullness in the upper abdomen after meals. Even if they only eat a small amount of food, they will also have symptoms such as abdominal pain, bloating, and acid reflux. If the intestinal tract mainly causes the inflammation of Hp, there will be such symptoms as a shapeless stool, unclean stool, and irregular defecation. 


Oral symptoms

Patients with Hp infection tend to accumulate large amounts of gas in the gastrointestinal tract, which moves up along the peristalsis of the stomach and enters into the mouth, resulting in relatively obvious halitosis. The halitosis caused by HP infection is different from the halitosis caused by oral diseases, which can be used as a basis for clinical diagnosis. 


Frequent hunger pangs:

Patients involuntarily reduce their food intake; due to a Hp infection can cause the stomach to swell. In addition, the ability to digest food and extract energy and nutrition from food is affected, so patients will have energy gaps, which lead to often manifested as obvious hunger, some patients will lose weight in a short period of time, physical decline, and even anemia symptoms. It is recommended that patients seek medical advice in time and exclude factors such as hyperthyroidism and diabetes before Hp infection can be diagnosed. 


Slobber:

Hp has a certain degree of bio-toxicity, which affects human nervous system. Therefore, patients may show the symptoms of excessive secretion of water, and the saliva of patients with a serious condition may spill out of the mouth involuntarily. It is recommended that patients seek medical treatment in time and consider whether there is Hp infection after excluding the influence of epilepsy, dementia, stroke, cerebral infarction and other factors. 


Although most Hp infected persons have no symptoms or complications, almost all Hp infected persons have chronic active gastritis. Therefore, in the fifth expert consensus, Hp gastritis is an infectious disease regardless of symptoms and/or complications, and the target of eradication treatment can be extended to asymptomatic patients. 


Recommendation of HP screening and testing products

Hp IgM / IgG antibodies joint detection kit (colloidal gold method, gxzz 20163400774), which is launched by Beijing Zhongjian Antai Diagnostic Technology Co., Ltd. National exclusive products make up for the lack of single IgG antibody detection index on the market. A drop of blood can complete rapid detection, eliminating the tedious process, and long waiting! 


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At present, there are hundreds of regular development units in China, among which the First Affiliated Hospital of Zhengzhou University and West China Hospital of Sichuan University have set a good example and played a leading role nationwide. 


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As the main project of Antai, after more than three years of publicity and promotion, both the medical institutions with strong academic atmosphere and the agents participating in HP training fully affirmed and praised the company for actively promoting Helicobacter pylori test and advocating gastric cancer screening and prevention. In the past three years, Antai has actively held and participated in more than 30 conferences related to immune-medicine in China, including the Academic Summit on marker immunity, Heilongjiang Investment Promotion Agency Conference, joint venture capital promotion conference and Shandong investment promotion conference, etc., focusing on the launch of the exclusive product of Antai HP IgM / IgG Antibodies joint detection kit, detection reagent with its distinct clinical significance and the superior performance of reagent, by the majority of dealers and end customers approval and support! 



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